Site gapA
- Name: gapA
- Type: Gene
- Synonyms
b1779 MG1655 locus tag gad - Mnemonic: glyceraldehyde phosphate deHase
- Left End Point: 40.09
- Right End Point: 40.10
- Products:
glyceraldehyde 3-phosphate dehydrogenase GAPDH-A - Direction: >
- Priority: 1
- 8 Alleles of This Gene
gapA1(Unst) gapA10::Tn10 gapA12(del)::Cm gapA2(Unst) gapA3 gapA5(ts) gapA7(ts) gapA791-YFP(::cat) - External Database Links:
Host Site Page Links NCBI/GenBank X02662 EcoGene.org EG10367 EcoliWiki gapA - Comment:
- Horizontal transfer? Sequence closer to eukaryotic GAPDH than to other prokaryotic GAPDH's. See epd as gapB.
- References:
- Branlant, G., C. Branlant 1985. Nucleotide sequence of the Escherichia coli gap gene. Different evolutionary behavior of the NAD+-binding domain and of the catalytic domain of D-glyceraldehyde-3-phosphate dehydrogenase. Eur.J.Biochem. 150:61-66
- Doolittle, R.F., D.F. Feng, K.L. Anderson, M.R. Alberro 1990. A naturally occurring horizontal gene transfer from a eukaryote to a prokaryote. J.Mol.Evol. 31:383-388
- Lawrence, J.G., H. Ochman, D.L. Hartl 1991. Molecular and evolutionary relationships among enteric bacteria. J.Gen.Microbiol. 137:1911-1921
- Nelson, K., T.S. Whittam, R.K. Selander 1991. Nucleotide polymorphism and evolution in the glyceraldehyde-3-phosphate dehydrogenase gene (gapA) in natural populations of Salmonella and Escherichia coli. Proc.Natl.Acad.Sci.USA 88:6667-6671
- Seta, F.D., S. Boschi-Muller, M.L. Vignais, G. Branlant 1997. Characterization of Escherichia coli strains with gapA and gapB genes deleted. J.Bacteriol. 179:5218-5221