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Site - cytRSite cytR Site cytR
- Name: cytR
- Type: Gene
- Synonyms
|
| b3934 | MG1655 locus tag |
- Mnemonic: Cytidine catabolism regulator
- Left End Point: 88.83
- Right End Point: 88.85
- Direction: <
- Properties:
| Property | Comment |
|---|
| autogenously regulated | CytR repressor |
| regulatory gene | for deo, udp and cdd |
- Priority: 1
- External Database Links:
- Comment:
- Regulatory gene for {\it deo} operon, {\it udp} and {\it cdd}. Selectable Phenotype. cytR^c: improved growth on uridine.
- References:
- Munch-Petersen, A., P. Nygaard, K. Hammer-Jespersen, N. Fiil 1972. Mutants constitutive for nucleoside-catabolizing enzymes in Escherichia coli K12. Eur.J.Biochem. 27:208-215
- Barbier, C.S., S.A. Short 1985. Studies on deo operon regulation in Escherichia coli: cloning and expression of the cytR structural gene. Gene 36:37-44
- Valentin-Hansen, P., J.E.L. Larson, P. Hojrup, S.A. Short, C.S. Barbier 1986. Nucleotide sequence of the CytR regulatory gene of E. coli K-12. Nucleic Acids Res. 14:2215-2228
- Sogaard-Andersen, L., H. Pedersen, B. Holst, P. Valentin-Hansen 1991. A novel function of the cAMP-CRP complex in Escherichia coli: cAMP-CRP functions as an adaptor for the CytR repressor in the deo operon. Mol.Microbiol. 5:969-975
- Rasmussen, P.B., B. Holst, P. Valentin-Hansen 1996. Dual-function regulators: the cAMP receptor protein and the CytR regulator can act either to repress or to activate transcription depending on the context. Proc.Natl.Acad.Sci.USA 93:10151-10155
