E. coli Genetic Resources at Yale
CGSC, The Coli Genetic Stock Center

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Site cvrA

• Name: cvrA
• Type: Gene
  Synonyms

  b1191	MG1655 locus tag
  ycgO

  
  
• Mnemonic: cell volume regulation
• Left End Point: 26.72
• Right End Point: 26.76
• Direction: >
• Priority: 0
  1 Alleles of This Gene

  cvrA781(del)::kan

  
  
• External Database Links:

  Host Site	Page Links
  EcoGene.org	EG13896
  EcoliWiki	cvrA

  
  
• Comment:
  • Required for growth at low osmolarity. Not involved in energy-dependent Na+ efflux. Proposed participant in cell volume regulation. Sequence homology to eukaryotic Na+/H+ exchangers.
• References:
  • Verkhovskaya, M.L., B. Barquera, M. Wikstrom 2001. Deletion of one of two Escherichia coli genes encoding putative Na+/H+ exchangers (ycgO) perturbs cytoplasmic alkali cation balance at low osmolarity. Microbiology 147:3005-3013