E. coli Genetic Resources at Yale
CGSC, The Coli Genetic Stock Center

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Site mak

• Name: mak
• Type: Gene
  Synonyms

  b0394	MG1655 locus tag
  yajF

  
  
• Mnemonic: MAnno(fructo)Kinase
• Left End Point: 8.82
• Right End Point: 8.84
  Products:

  manno (fructose) kinase

  
  
• Direction: >
• Priority: 0
  1 Alleles of This Gene

  mak-759(del)::kan

  
  
• External Database Links:

  Host Site	Page Links
  EcoGene.org	EG11288
  EcoliWiki	mak

  
  
• Comment:
  • mak-0 phenotype = unable to use fructose via phospoenolpyruvate phophotransferase system. mak(+) phenotype = further mutation to permit growth on ketose by derepression of a manno (fructose) kinase.
• References:
  • Sproul, A.A., L.T. Lambourne, D.J. Jean-Jacques, H.L. Kornberg 2001. Genetic control of manno(fructo)kinase activity in Escherichia coli. Proc.Natl.Acad.Sci.USA 98:15257-15259