About the CGSC
Searching the CGSC Database
How to Request Strains or Information
Site - gltASite gltA Site gltA
- Name: gltA
- Type: Gene
- Synonyms
|
| b0720 | MG1655 locus tag |
| glut | |
| icdB | Helling,1995 |
- Mnemonic: Glutamate
- Left End Point: 16.22
- Right End Point: 16.25
- Direction: <
- Priority: 1
- External Database Links:
- Comment:
- Selectable Phenotype. Loss, in icd-: fast growth. gltA- cells, deficient in citrate synthase, require glutamate or proline for growth (Lakshmi and Helling, below).
- References:
- Lakshmi, TM, RB Helling 1976. Selection for citrate synthase deficiency in icd mutants of Escherichia coli. J. Bacteriol. 127(1):76-83.
- Guest, J.R. 1981. Hybrid plasmids containing the citrate synthase gene (gltA) of Escherichia coli K-12. J.Gen.Microbiol. 124:17-23
- Spencer, M.E., J.R. Guest 1982. Molecular cloning of four tricarboxylic acid cycle genes of Escherichia coli. J.Bacteriol. 151:542-552
- Ner, S.S., V. Bhayana, A.W. Bell, I.G. Giles, H.W. Duckworth, D.P. Bloxham 1983. Complete sequence of the gltA gene encoding citrate synthase in Escherichia coli. Biochemistry 22:5243-5249
- Hull, E.P., M.E. Spencer, D. Wood, J.R. Guest 1983. Nucleotide sequence of the promoter region of the citrate synthase gene (gltA) of Escherichia coli. FEBS Lett. 156:366-370
- Bloxham, D.P., C.J. Herbert, I.G. Giles, S.S. Ner 1983. The use of bacteriophage M13 carrying defined fragments of the Escherichia coli gltA gene to determine the location and structure of the citrate synthase promoter region. Mol.Gen.Genet. 191:499-50
- Wood, D., M.G. Darlison, R.J. Wilde, J.R. Guest 1984. Nucleotide sequence encoding the flavoprotein and hydrophobic subunits of the succinate dehydrogenase of Escherichia coli. Biochem.J. 222:519-534
- Wilde, R.J., J.R. Guest 1986. Transcript analysis of the citrate synthase and succinate dehydrogenase genes of Escherichia coli. J.Gen.Microbiol. 132:3239-3251
- Park, S.J., J. McCabe, J. Turna, R.P. Gunsalus 1994. Regulation of the citrate synthase (gltA) gene of Escherichia coli in response to anaerobiosis and carbon supply: role of the arcA gene product. J.Bacteriol. 176:5086-5092
- Helling, RB 1995. icdB mutants of Escherichia coli. J. Bacteriol. 177(9):2592-3.
