Site guaB
- Name: guaB
- Type: Gene
- Synonyms
b2508 MG1655 locus tag guaR ? - Mnemonic: Guanine
- Left End Point: 56.70
- Right End Point: 56.74
- Products:
IMP dehydrogenase inosine monophosphate dehydrogenase - Direction: <
- Priority: 1
- 4 Alleles of This Gene
guaB22 guaB24 guaB27 guaB757(del)::kan - External Database Links:
Host Site Page Links EcoGene.org EG10421 EcoliWiki guaB - Comment:
- Selectable phenotype. Loss: 5-fluorouracil + 5-fluorouridine resistance. guaR described by Tiedeman and Smith MGG 195:77 (1984); p.c. to Rudd indicated that it didn't exist as separate gene.
- References:
- Udaka, S., H.S. Moyed 1963. Inhibition of parental and mutant xanthosine 5--phosphate aminases by psicofuranine. J.Biol.Chem. 238:2797-2803
- Thomas, M.S., W.T. Drabble 1984. Molecular cloning and characterization of the gua regulatory region of Escherichia coli K12. Mol.Gen.Genet. 195:238-245
- Tiedeman, A., J.M. Smith 1985. Nucleotide sequence of the guaB locus encoding IMP dehydrogenase of Escherichia coli K12. Nucleic Acids Res. 13:1303-1316
- Thomas, M.S., W.T. Drabble 1985. Nucleotide sequence and organization of the gua promoter region of Escherichia coli. Gene 36:45-53
- Tesfa-Selase, F., W.T. Drabble 1992. Regulation of the gua operon of Escherichia coli by the DnaA protein. Mol.Gen.Genet. 231:256-264
- Davies, I.J., W.T. Drabble 1996. Stringent and growth-rate-dependent control of the gua operon of Escherichia coli K-12. Microbiology 142:2429-2437