Site iclR
- Name: iclR
- Type: Gene                          - Synonyms
b4018 MG1655 locus tag 
- Mnemonic: isocitrate lyase
- Left End Point: 90.97
- Right End Point: 90.99- Products:
repressor of aceBA (isocitrate lyase, malate synthase A) 
- Direction: <
- Priority: 1- 5 Alleles of This Gene
iclR13 iclR15(Const) iclR17(Const) iclR7(Const) iclR785(del)::kan 
- External Database Links:Host Site Page Links NCBI/GenBank M31761 EcoGene.org EG10491 EcoliWiki iclR 
- Comment: - iclR^c: stronger growth on butyrate and valerate. Can be selected in ppc-background by growth on glucose or glycerol.
 
- References: - Pauli, G., P. Overath 1972. ato operon: a highly inducible system for acetoacetate and butyrate degradation in Escherichia coli. Eur.J.Biochem. 29:553-562
- Maloy, S.R., W.D. Nunn 1982. Genetic regulation of the glyoxylate shunt in Escherichia coli K-12. J.Bacteriol. 149:173-180
- Sunnarborg, A., D.J. Klumpp, T. Chung, D.C. LaPorte 1990. Regulation of the glyoxylate bypass operon: cloning and characterization of iclR. J.Bacteriol. 172:2642-2649
- Cortay, J.C., D. Negre, A. Galinier, B. Duclos, G. Perriere, A.J. Cozzone 1991. Regulation of the acetate operon in Escherichia coli: purification and functional characterization of the IclR repressor. EMBO J. 10:675-679
- Fujita, N., H. Mori, T. Yura, A. Ishihama 1994. Systematic sequencing of the Escherichia coli genome: analysis of the 2.4-4.1 min (110,917-193,643 bp) region. Nucleic Acids Res. 22:1637-1639
 
