E. coli Genetic Resources at Yale
CGSC, The Coli Genetic Stock Center

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Site ddpX

• Name: ddpX
• Type: Gene
  Synonyms

  b1488	Blattner seq
  b1488	MG1655 locus tag
  vanX
  yddT	Rudd

  
  
• Mnemonic: D,D-dipeptide permease
• Left End Point: 33.64
• Right End Point: 33.65
  Products:

  D-Alanine-D-Alanine dipeptidase

  VanX homolog

  
  
• Direction: <
• Priority: 0
  1 Alleles of This Gene

  ddpX781(del)::kan

  
  
• External Database Links:

  Host Site	Page Links
  EcoGene.org	EG13791
  EcoliWiki	ddpX

  
  
• Comment:
  • Homolog of vancomycin resistance gene VanX in gram-positives, which requires expr. of vanRSHA also to produce peptidoglycan chain precursors with altered termini. E.coli impermeable to Van.
• References:
  • Lessard, I.A.D., S.D. Pratt, D.G. McCafferty, D.E. Bussiere, C. Hutchins, B.L. Wanner, L. Katz, C.T. Walsh 1998. Homologs of the vancomycin resistance D-Ala-D-Ala dipeptidase VanX in Streptomyces toyocaensis, Escherichia coli and Synechocystis: attribu