E. coli Genetic Resources at Yale
CGSC, The Coli Genetic Stock Center

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Site mdaB

• Name: mdaB
• Type: Gene
  Synonyms

  b3028	MG1655 locus tag

  
  
• Mnemonic: modulator of drug activity
• Left End Point: 68.34
• Right End Point: 68.35
• Direction: >
• Priority: 0
  1 Alleles of This Gene

  mdaB726(del)::kan

  
  
• External Database Links:

  Host Site	Page Links
  EcoGene.org	EG12656
  EcoliWiki	mdaB

  
  
• Comment:
  • resistance to DMP840, adraimycin and etoposide; possibly modulates topo IV activity. upstream of ygiN and coupled with ygiN minimizes quinone toxicity.
• References:
  • Chatterjee, P.K., N.L. Sternberg 1995. A general genetic approach in Escherichia coli for determining the mechanisms of action of tumoricidal agents: application to DMP 840, a tumoricidal agent. Proc.Natl.Acad.Sci.USA 92:8950-8954