Site slyD
- Name: slyD
- Type: Gene
- Synonyms
b3349 MG1655 locus tag - Mnemonic: sensitivity to lysis
- Left End Point: 74.92
- Right End Point: 74.93
- Products:
FK-506-BP-like lysis protein for phiX174 metal ion-regulated peptidyl-prolyl cis/trans-isomerase - Direction: <
- Priority: 0
- 3 Alleles of This Gene
slyD1(NOTinSC) slyD738(del)::kan slyD791-YFP(::cat) - External Database Links:
Host Site Page Links EcoGene.org EG11663 EcoliWiki slyD - Comment:
- overexpression causes filamentation. Has 14 histidines in C-terminal domain. {\it slyD1} mutant available from Ryland Young or Invitrogen.
- References:
- Roof, W.D., S.M. Horne, K.D. Young, R. Young 1994. slyD, a host gene required for phi X174 lysis, is related to the FK506-binding protein family of peptidyl-prolyl cis-trans-isomerases. J.Biol.Chem. 269:2902-2910
- Wulfing, C., J. Lombardero, A. Pluckthun 1994. An Escherichia coli protein consisting of a domain homologous to FK506-binding proteins (FKBP) and a new metal binding motif. J.Biol.Chem. 269:2895-2901
- Horne, S.M., K.D. Young 1995. Escherichia coli and other species of the Enterobacteriaceae encode a protein similar to the family of Mip-like FK506-binding proteins. Arch.Microbiol. 163:357-365
- Hottenrott, S., T. Schumann, A. Pluckthun, G. Fischer, J.U. Rahfeld 1997. The Escherichia coli SlyD is a metal ion-regulated peptidyl-prolyl cis/trans-isomerase. J.Biol.Chem. 272:15697-15701
- Roof, W.D., H.Q. Fang, K.D. Young, J. Sun, R. Young 1997. Mutational analysis of slyD, an Escherichia coli gene encoding a protein of the FKBP immunophilin family. Mol.Microbiol. 25:1031-1046