E. coli Genetic Resources at Yale
CGSC, The Coli Genetic Stock Center

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Site emrB

• Name: emrB
• Type: Gene
  Synonyms

  b2686	MG1655 locus tag

  
  
• Mnemonic: e-multidrug resistance
• Left End Point: 60.58
• Right End Point: 60.62
• Direction: >
• Properties:

  Property	Comment
  encodes membrane protein	NULL

  
  
• Priority: 0
  1 Alleles of This Gene

  emrB767(del)::kan

  
  
• External Database Links:

  Host Site	Page Links
  EcoGene.org	EG11439
  EcoliWiki	emrB

  
  
• Comment:
  • hydrophobic, 14 potential alpha-helices to span inner membrane. homol.to Qac, multidrug-resistant pump, family, incl. tetR pumps of Gram-pos and gal/H+ symporter of coli
• References:
  • Lomovskaya, O.L., K. Lewis 1992. Emr, an Escherichia coli locus for multidrug resistance. Proc.Natl.Acad.Sci.USA 89:8938-8942
  
  
  • Lomovskaya, O., F. Kawai, A. Matin 1996. Differential regulation of the mcb and emr operons of Escherichia coli: role of mcb in multidrug resistance. Antimicrob.Agents Chemother. 40:1050-1052