Site mprA
- Name: mprA
- Type: Gene
- Synonyms
b2684 MG1655 locus tag emrR Lomovskaya et al. - Mnemonic: microcin peptide regulation
- Left End Point: 60.54
- Right End Point: 60.55
- Direction: >
- Properties:
Property Comment regulatory gene negative regulator of EmrAB - Priority: 0
- 1 Alleles of This Gene
mprA765(del)::kan - External Database Links:
Host Site Page Links EcoGene.org EG10603 EcoliWiki mprA - Comment:
- In high copy,the gene reduces the synth.of microcin B17 and C7, plasmid-determined peptide antibiotics produced by coli at stat.phase,and blocks osmosinduction of proU.Neg.regulator of emrAB
- References:
- del Castillo, I., J.M. Gomez, F. Moreno 1990. mprA, an Escherichia coli gene that reduces growth-phase-dependent synthesis of microcins B17 and C7 and blocks osmoinduction of proU when cloned on a high-copy-number plasmid. J.Bacteriol. 172:437-445
- del Castillo, I., J.E. Gonzalez-Pastor, J.L. San Millan, F. Moreno 1991. Nucleotide sequence of the Escherichia coli regulatory gene mprA and construction and characterization of mprA-deficient mutants. J.Bacteriol. 173:3924-3929
- Lomovskaya, O.L., K. Lewis, A. Matin 1995. EmrR is a negative regulator of the Escherichia coli multidrug resistance pump EmrAB. J.Bacteriol. 177:2328-2334