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Site - topBSite topB Site topB
- Name: topB
- Type: Gene
- Synonyms
|
| b1763 | MG1655 locus tag |
| mutR | Whoriskey et al. |
- Mnemonic: topoisomerase
- Left End Point: 39.73
- Right End Point: 39.77
- Direction: <
- Priority: 0
- External Database Links:
- Comment:
- Can also act as an RNA topoisomerase
- References:
- DiGate, R.J., K.J. Marians 1989. Molecular cloning and DNA sequence analysis of Escherichia coli topB, the gene encoding topoisomerase III. J.Biol.Chem. 264:17924-17930
- Whoriskey, S.K., M.A. Schofield, J.H. Miller 1991. Isolation and characterization of Escherichia coli mutants with altered rates of deletion formation. Genetics 127:21-30
- Schofield, M.A., R. Agbunag, M.L. Michaels, J.H. Miller 1992. Cloning and sequencing of Escherichia coli mutR shows its identity to topB, encoding topoisomerase III. J.Bacteriol. 174:5168-5170
- Zhang, H.L., S. Malpure, R.J. DiGate 1995. Escherichia coli DNA topoisomerase III is a site-specific DNA binding protein that binds asymmetrically to its cleavage site. J.Biol.Chem. 270:23700-23705
- Wang, H., R.J. Di Gate, N.C. Seeman 1996. An RNA topoisomerase. Proc.Natl.Acad.Sci.USA 93:9477-9482
- Uematsu, N., S. Eda, K. Yamamoto 1997. An Escherichia coli topB mutant increases deletion and frameshift mutations in the supF target gene. Mutat.Res. 383:223-230
