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Site - araCSite araC Site araC
- Name: araC
- Type: Gene
- Synonyms
|
| b0064 | MG1655 locus tag |
- Mnemonic: Arabinose
- Left End Point: 1.52
- Right End Point: 1.54
- Direction: >
- Properties:
| Property | Comment |
|---|
| regulatory gene | NULL |
- Priority: 1
- External Database Links:
- Comment:
- Regulatory gene; activator and repressor protein. Selectable Pheno. araC^c: growth on arabinose + fucose. araC-, in araC^c: ribitol resistance. for B/r, Miyada et al. PNAS 75:4727(1978)
- References:
- Englesberg, E., J. Irr, J. Power, N. Lee 1965. Positive control of enzyme synthesis by gene C in the L-arabinose system. J.Bacteriol. 90:946-957
- Katz, L. 1970. Selection of araB and araC mutants of Escherichia coli B/r by resistance to ribitol. J.Bacteriol. 102:593-595
- Smith, B.R., R. Schleif 1978. Nucleotide sequence of the L-arabinose regulatory region of Escherichia coli K12. J.Biol.Chem. 253:6931-6933
- Ogden, S., D. Haggerty, C.M. Stoner, D. Kolodrubetz, R. Schleif 1980. The Escherichia coli L-arabinose operon: binding sites of the regulatory proteins and a mechanism of positive and negative regulation. Proc.Natl.Acad.Sci.USA 77:3346-3350
- Miyada, C.G., A.H. Horwitz, L.G. Cass, J. Timko, G. Wilcox 1980. DNA sequence of the araC regulatory gene from Escherichia coli B/r. Nucleic Acids Res. 8:5267-5274
- Wallace, R.G., N. Lee, A.V. Fowler 1980. The araC gene of Escherichia coli: transcriptional and translational start-points and complete nucleotide sequence. Gene 12:179-190
- Cass, L.G., A.H. Horwitz, C.G. Miyada, L. Greenfield, G. Wilcox 1980. The araC regulatory gene mRNA contains a leader sequence. Mol.Gen.Genet. 180:219-226
- Lee, N., W. Gielow, R.G. Wallace 1981. Mechanism of araC autoregulation and the domains of two overlapping promoters, Pc and Pbad, in the L-arabinose regulatory region of Escherichia coli. Proc.Natl.Acad.Sci.USA 78:752-756
- Kolodrubetz, D., R. Schleif 1981. Regulation of the L-arabinose transport operons in Escherichia coli. J.Mol.Biol. 151:215-227
- Stoner, C.M., R. Schleif 1982. Is the amino acid but not the nucleotide sequence of the Escherichia coli araC gene conserved?. J.Mol.Biol. 154:649-652
- Dunn, T.M., R. Schleif 1984. Deletion analysis of the Escherichia coli ara P_C and P_BAD promoters. J.Mol.Biol. 180:201-204
- Sheppard, D.E. 1986. Dominance relationships among mutant alleles of regulatory gene araC in the Escherichia coli B/R L-arabinose operon. J.Bacteriol. 168:999-1001
- Carra, J.H., R.F. Schleif 1993. Variation of half-site organization and DNA looping by AraC protein. EMBO J. 12:35-44
