Product L-isoaspartyl protein carboxyl methyltransferase
| L-isoaspartyl protein carboxyl methyltransferase |
| PIMT, protein-L-isoaspartate(D-aspartate) O-methyltransferase |
catalyses the methyl esterification of L-isoaspartyl residues formed in spont. degradation rxs. to convert to normal aspartyl configuration. repairs age-damaged proteins?
- Fu, J.C., L. Ding, S. Clarke 1991. Purification, gene cloning, and sequence analysis of an L-isoaspartyl protein carboxyl methyltransferase from Escherichia coli. J.Biol.Chem. 266:14562-14572
- Li, C., S. Clarke 1992. A protein methyltransferase specific for altered aspartyl residues is important in Escherichia coli stationary-phase survival and heat-shock resistance. Proc.Natl.Acad.Sci.USA 89:9885-9889
- David, C.L., J. Keener, D.W. Aswad 1999. Isoaspartate in ribosomal protein S11 of Escherichia coli. J.Bacteriol. 181:2872-2877