Product porphobilinogen deaminase
| porphobilinogen deaminase |
| pre-uroporphyrinogen I synthase |
| hydroxymethylbilane synthase |
| Host Site | Page Links |
|---|---|
| EcoCyc | OHMETHYLBILANESYN-MONOMER |
cleaves A/G- or dihydro-oxo-G-containing DNA on the A-strand by N-glycosylase and apurinic/apyrimidinic endonuclease or lyase activities.
- Lander, M., A.R. Pitt, P.R. Alefounder, C. Abell, A.R. Battersby 1991. Studies on the mechanism of hydroxymethylbilane synthase concerning the role of arginine residues in substrate binding. Biochem.J. 275:447-452
- Shoolingin-Jordan, P.M. 1995. Porphobilinogen deaminase and uroporphyrinogen III synthase: structure, molecular biology, and mechanism. J.Bioenerg.Biomembr. 27:181-195
- Lu, A.L., D.S. Yuen, J. Cillo 1996. Catalytic mechanism and DNA substrate recognition of Escherichia coli MutY protein. J.Biol.Chem. 271:24138-24143
- Louie, G.V., P.D. Brownlie, R. Lambert, J.B. Cooper, T.L. Blundell, S.P. Wood, V.N. Malashkevich, A. Hadener, M.J. Warren, P.M. Shoolingin-Jordan 1996. The three-dimensional structure of Escherichia coli porphobilinogen deaminase at 1.76-A resolution.