E. coli Genetic Resources at Yale
CGSC, The Coli Genetic Stock Center

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Mutation pgsA10

• Name: pgsA10
• Type: Base Pair Substitution
• Mutation of Gene: pgsA
• Approx. Map Location: 42.90
• Comments
  • Ref. below shows mutation substitutes a T for the C in an ACA (Thr) codon of pgsA10, substituting Ile in hydrophob.reg. Lowers in vitro PGP synthase act. but not acidic-phospholipid synthesis in vivo.
• References
  • Usui, M., H. Sembongi, H. Matsuzaki, K. Matsumoto, I. Shibuya 1994. Primary structures of the wild-type and mutant alleles encoding the phosphatidylglycerophosphate synthase of Escherichia coli. J.Bacteriol. 176:3389-3392
• 1 Strains Carrying This Mutation

  Name	Mutations	Genotype
  R477-100	14	F-, thr-1, araC14, leuB6(Am), fhuA1, lacY1, tsx-78, Δ(galK-attLAM)99, pgsA10, hisG4(Oc), rfbC1, rpsL136(strR), xylA5, mtl-1, thiE1