E. coli Genetic Resources at Yale
CGSC, The Coli Genetic Stock Center

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Mutation lacZ575

• Name: lacZ575
• Type: Base Pair Substitution
• Mutation of Gene: lacZ
• Approx. Map Location: 7.81
• Comments
  • is a basepair mutation, A to T, in codon Glu-461 (GAG), which results in substitution of valine for glutamic acid at this position within active site of lacZ gene on the F-prime.
• References
  • Cupples, C.G., J.H. Miller 1989. A set of lacZ mutations in Escherichia coli that allow rapid detection of each of the six base substitutions. Proc.Natl.Acad.Sci.USA 86:5345-5349