E. coli Genetic Resources at Yale
CGSC, The Coli Genetic Stock Center

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Mutation marR11

• Name: marR11
• Type: Deletion
• Mutation of Gene: marR
• Approx. Map Location: 34.86
• Comments
  • :Temporary allele number assignment. Mutation deletes bp 1481-1485 of marR (Cohen et al. 1993) and results in overexpression of marRAB operon and multiple antibiotic resistance.
• References
  • Oethinger, M, WV Kern, AS Jellen-Ritter, LM McMurry, SB Levy 2000. Ineffectiveness of topoisomerase mutations in mediating clinically significant fluoroquinolone resistance in Escherichia coli in the absence of the AcrAB efflux pump. Antimicrob. Agents Chemother. 44(1):10-3.
• 1 Strains Carrying This Mutation

  Name	Mutations	Genotype
  AG112	9	F-, glnX44(AS), galK2(Oc), λ-, Δ(bioC-uvrB), marR11, rpsL704(strR), mtl-1, argE3(Oc), thiE1