Mutation trpC721(trpF(del))
- Name: trpC721(trpF(del))
- Type: Deletion
- Mutation of Gene: trpC
- Approx. Map Location: 28.38
- Properties
Property Symbol del.of PRA Isomerase (F) dom. trpF(del) - Comments
- : This mutation deletes the TrpF, PRA isomerase, portion of the trpC gene, leaving an artifically monofunctional IGP synthase gene. (C.Yanofsky Lab)
- References
- Sterner, R., A. Dahm, B. Darimont, A. Ivens, W. Liebl, K. Kirschner 1995. (beta-alpha)8-barrel proteins of tryptophan biosynthesis in the hyperthermophile Thermotoga maritima. EMBO J. 14:4395-4402
- Darimont, B., C. Stehlin, H. Szadkowski, K. Kirschner 1998. Mutational analysis of the active site of indoleglycerol phosphate synthase from Escherichia coli. Protein Sci 7:1221-1232
- 1 Strains Carrying This Mutation
Name Mutations Genotype JMB9hsdR-M+Δ(trpF) 12 F-, thr-1, araC14, leuB6(Am), glnX44(AS), galK0, λ-, ΔtrpC721(trpF), xylA5, mtl-1, thiE1, hsdR2, hsdR-