Mutation nadD72(ts,Fs)

Name: nadD72(ts,Fs)
Type: Deletion
Mutation of Gene: nadD
Approx. Map Location: 14.42
Synonyms
Designation Where Used
fusB72
Properties
Property Symbol
Frameshift mutation Fs
Temperature Sensitive ts
Comments
- This allele has a deletion of base T-613 causing a -1 frameshift that leads to a change of the last 10 amino acids and an addition of 17 amino acids.
- This allele produces very little NAD+ and NADPH at 30 deg. C and essentially none at 42 deg. C.
References
- Stancek, M, LA Isaksson, M Ryden-Aulin 2003. fusB is an allele of nadD, encoding nicotinate mononucleotide adenylyltransferase in Escherichia coli Microbiology (Reading, Engl.) 149(Pt 9):2427-2433.
1 Strains Carrying This Mutation
Name Mutations Genotype
UQ72 4 F-, lacZ4, nadD72(ts,Fs), λ^-, argG75

Property	Symbol
Frameshift mutation	Fs
Temperature Sensitive	ts

E. coli Genetic Resources at Yale CGSC, The Coli Genetic Stock Center