E. coli Genetic Resources at Yale
CGSC, The Coli Genetic Stock Center

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Mutation lexA51

• Name: lexA51
• Type: Deletion
• Mutation of Gene: lexA
• Approx. Map Location: 91.71
• Synonyms

  Designation	Where Used
  spr-51

  
  
• Comments
  • : defective LexA resulting in constitutive expression of LexA-repressed genes. Formerly called spr-51
  • This is a frameshift mutation from an single A deletion between bases 475 and 480
• References
  • Fernandez De Henestrosa, A.R., T. Ogi, S. Aoyagi, D. Chafin, J.J. Hayes, H. Ohmori, R. Woodgate 2000. Identification of additional genes belonging to the LexA regulon in Escherichia coli. Mol.Microbiol. 35:1560-1572
• 2 Strains Carrying This Mutation

  Name	Mutations	Genotype
  DM1415	16	F-, thr-1, araC14, leuB6(Am), Δ(gpt-proA)62, tsx-33?, glnX44(AS), galK2(Oc), λ-, sulA211, recA1, rpsL31(strR), xylA5, mtl-1, thiE1?, lexA3(Ind-), lexA51
  DM1187	17	F-, thr-1, araC14, leuB6(Am), Δ(gpt-proA)62, tsx-33?, glnX44(AS), galK2(Oc), λ-, sulA211, hisG4(Oc), recA441(ts), rpsL31(strR), xylA5, mtl-1, thiE1?, lexA51, lexA3(Ind-)