CGSC Strain#: 3599
Strain Designation: 58-278M      Source of Strain: P. Treffers
Other Designations: T94A
Sex: F+ Chromosomal Markers: mutT1, bio-1(Unst), spoT1, phe-1
Strain Comments:

• bio-1 is unstable.
• mutT1-- probable defect is IS1 insertion into WT gene
• bio-1(Unst)-- : This marker apparently reverts at high frequency
• spoT1-- In addition to the 6bp insertion, there is a C to T transition resulting in an H257Y substitution.
• Unst = unstable

References:

• Lederberg, J 1949. Aberrant Heterozygotes in Escherichia Coli. 35(4):178-84.
• Treffers, P., V. Spinelli, N.O. Belser 1954. A factor (or mutator gene) influencing mutation rates in Escherichia coli. Proc.Natl.Acad.Sci.USA 40:1064-1071
• Skaar, P.D. 1956. A binary mutability system in Escherichia coli. Proc.Natl.Acad.Sci.USA 42:245-249
• Cox, E.C., C. Yanofsky 1969. Mutator gene studies in Escherichia coli. J.Bacteriol. 100:390-397